SQL Server 2008 can generate compressed database backup files in
the Enterprise Edition, while SQL Server 2008 R2 introduced that
feature in the Standard Edition. Do you then need 3rd party
compression backup software?
I guess it pretty much depends on whether the value added
features provided by those software is worth the extra cost to you.
Since I work daily on Red Gate's SQL Backup product, I'll touch
on some features available in that product, that goes beyond just
compression.